This course is part of PrimaryCareNow: Live on August 19-21, 2026.
Diagram of a glutamate synapse relevant to major depressive disorder (MDD) and PCN pharmacology. An inhibitory interneuron releases GABA onto a receptor on the presynaptic neuron, which also contains a Sigma-1 receptor and vesicles of glutamate. The presynaptic terminal releases glutamate into the synapse, where it acts on postsynaptic NMDA and AMPA receptors, labeled as ionotropic (rapid-acting) glutamate receptors.

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Industry Webcast

One Patient's Journey: A Rapid-Acting Antidepressant that Modulates Glutamate, Sigma-1, and Monoaminergic PathwaysIndustry Webcast Sponsored by Axsome Therapeutics, Inc.; Not for CME/CE Credit

This program will highlight the current unmet needs in MDD and present a treatment option with rapid symptom improvement for adult patients with MDD.

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CME/CE Information

0 Credits - Not for CME/CE Credit

Release Date: 8/19/2026

Expiration Date: 8/19/2026

Topics

Faculty

Faculty

Michelle Scargle, MD

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Industry Sponsor

Axsome Therapeutics, Inc.

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One Patient's Journey: A Rapid-Acting Antidepressant that Modulates Glutamate, Sigma-1, and Monoaminergic Pathways

Register